Product Name :
R788
Description:
Fostamatinib, also known as R 788 and R-935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. Fostamatinib is also a pro-drug of R-406. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage.
CAS:
901119-35-5
Molecular Weight:
580.46
Formula:
C23H26FN6O9P
Chemical Name:
{[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-4-yl]methoxy}phosphonic acid
Smiles :
CC1(C)OC2=CC=C(NC3=NC(NC4C=C(OC)C(OC)=C(C=4)OC)=NC=C3F)N=C2N(COP(O)(O)=O)C1=O
InChiKey:
GKDRMWXFWHEQQT-UHFFFAOYSA-N
InChi :
InChI=1S/C23H26FN6O9P/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Fostamatinib, also known as R 788 and R-935788, is an orally active, potent and selective Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities. Fostamatinib is also a pro-drug of R-406. Fostamatinib inhibits Syk kinase-mediated IgG Fc gamma receptor signaling, resulting in inhibition of the activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage.{{Tolvaptan} MedChemExpress|{Tolvaptan} Autophagy|{Tolvaptan} Technical Information|{Tolvaptan} Purity|{Tolvaptan} custom synthesis|{Tolvaptan} Cancer} |Product information|CAS Number: 901119-35-5|Molecular Weight: 580.{{Sonelokimab} MedChemExpress|{Sonelokimab} Interleukin Related|{Sonelokimab} Technical Information|{Sonelokimab} In stock|{Sonelokimab} supplier|{Sonelokimab} Autophagy} 46|Formula: C23H26FN6O9P|Chemical Name: {[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-4-yl]methoxy}phosphonic acid|Smiles: CC1(C)OC2=CC=C(NC3=NC(NC4C=C(OC)C(OC)=C(C=4)OC)=NC=C3F)N=C2N(COP(O)(O)=O)C1=O|InChiKey: GKDRMWXFWHEQQT-UHFFFAOYSA-N|InChi: InChI=1S/C23H26FN6O9P/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:25818744 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
