Product Name :
PNU-120596
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
311.7
Solubility :
Soluble in DMSO (50mg/ml); slightly soluble in methanol (1mg/ml) or acetonitrile (0.5mg/ml).
Appearance:
White to off-white solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended.
Description:
Nicotinic acetylcholine receptor activator Type II positive allosteric modulator (PAM) of α7 neuronal nicotinic acetylcholine receptor (nAChR) (EC50=216nM). Shows no detectable effect on α4β2, α3β4 and α9α10 receptors.
CAS :
501925-31-1
Solubility:
Soluble in DMSO (50mg/ml); slightly soluble in methanol (1mg/ml) or acetonitrile (0.{{2687970-96-1} web|{2687970-96-1} Technical Information|{2687970-96-1} In Vivo|{2687970-96-1} supplier} 5mg/ml).
Formula:
C13H14ClN3O4
Additional Information :
| Alternative Name NSC 216666, N-(5-Chloro-2,4-dimethoxyphenyl)-N’-(5-methyl-3-isoxazolyl)urea | Appearance White to off-white solid.{{1349723-93-8} web|{1349723-93-8} Purity & Documentation|{1349723-93-8} In Vivo|{1349723-93-8} custom synthesis} | CAS 501925-31-1 | Couple Target Acetylcholine receptor | Couple Type Activator | Formula C13H14ClN3O4 | Identity Determined by MS and NMR.PMID:30480946 | MW 311.7 | Purity ≥98% (HPLC) | Solubility Soluble in DMSO (50mg/ml); slightly soluble in methanol (1mg/ml) or acetonitrile (0.5mg/ml). | Unit of Measure (UM) mg
