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Stat3 monoclonal antibody (7G8)
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Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes. Western blot analysis of Stat3 Lane 1: MW, Lane 2: A431, Lane 3:HeLa, Lane 4: NIH-3T3. Western blot analysis of Stat3 Lane 1: MW, Lane 2: A431, Lane 3:HeLa, Lane 4: NIH-3T3.
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| Alternative Name Signal transducer and activator of transcription 3 | Application WB | Application Notes Detects a band of ~88kDa by Western blot. | Clone 7G8 | Formulation Liquid.1029044-16-3 Data Sheet In PBS, pH 7.2244235-49-0 Data Sheet 2, containing BSA, 0.PMID:25905356 09% sodium azide, and 50% glycerol. | Host Mouse | Immunogen Recombinant full length human Stat3. | Recommendation Dilutions/Conditions Western Blot (1µg/ml, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. | Source Purified from mouse ascites. | Species Reactivity Human, Mouse, Rat | UniProt ID P40763 | Unit of Measure (UM) µg
