Product Name: Anti-EGFR (Epidermal Growth Factor Receptor) Antibody
Description: This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (
Target:
Conjugate:
Product Category: Mouse Monoclonal Antibody
Immunogen: Recombinant extracellular domain of human EGFR protein
Host:
Isotype: IgG2a, kappa
Form:
CAS NO: 157009-81-9
Product: GPRP (acetate)
Applications: Flow Cytometry (0.5-1ug/million cells in 0.1ml)Immunofluorescence (1-2ug/ml)Immunohistology (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min
Reactivity: Human. Does not react with mouse. Others not known.
Working Dilution:
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Species:
Synonyms: Erbb1, ERBB1, Errp, HER1, mENA, PIG61, Proto-oncogene c-ErbB-1, Receptor Tyrosine Protein Kinase, ErbB1, Urogastrone, wa2, Wa5
Background:
Molecular Weight: ~170kDa (wild type) and ~145kDa (vIII variant)
Purity:
Image Description:
PubMed ID:http://aac.asm.org/content/44/11/3097.abstract
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