Finally, other classified proteins include those that share common functions in antioxidation and free-radical removal include isomerases

Underneath the classification of metabolisms, we identified proteins belonging to the glycolysis pathway [phosphoglycerate kinase 1 (PGK1), enolase one (ENO1), aldolase A (ALDOA), pyruvate kinase (PKM2), glucose phosphate isomerase (GPI), triosephosphate isomerase, (TPI1)], tricarboxylic acid cycle [citrate synthase (CS), aconitase 2 (ACO2), malate dehydrogenase two (MDH2)], amino acid metabolic process [(aldehyde dehydrogenase 18 family members, member A1 (ALDH18A1)], purine metabolic rate [IMP dehydrogenase (IMPDH2), adenylate kinase two(AK2)], porphyrin fat burning capacity [HMOX2 (heme oxygenase)], and fatty acid/lipid/steroid metabolic process [farnesyl-diphosphate farnesyltransferase 1 (FDFT1), annexin A1 (ANXA1)]. Well worth noting is a team of sign transduction proteins. Among them, though only fourteen-3-three theta polypeptide (YWHAQ) is labeled exclusively in sign transduction a number of proteins are classified in other categories but often are linked with different signaling transduction pathways, like integrin signaling [integrin (ITGB4, ITGA6) filamin (FLNA, FLNB, FLNC), actinin alpha 1, four (ACTN1, ACTN4)], cadherin signaling [a-catenin (CTNNA1)], EGF signaling (epidermal progress factor receptor (EGFR), FAS signaling [lamin (LMNA, LMNB1)], as well as the and the tumor suppressor maspin (SERPINB5). Some are involved in DNA replication [proliferating mobile nuclear antigen (PCNA), X-ray restore complementing faulty fix (XRCC5)], cell-cycle regulation and mobile proliferation [N-myc Food Yellow 3 structure downstreamregulated 1 (NDRG1)], protein phosphorylation [protein phosphatase 1G (2C) (PPM1G)], as nicely as mobile adhesion and induction of apoptosis [galectin 1 (LGALS1), glyceraldehyde-3-phosphate dehydrogenase GAPDH]. Lastly, other categorised proteins include people that share frequent functions in antioxidation and free of charge-radical elimination include isomerases [peroxiredoxin (PRDX1, PRDX5), protein disulfide-isomerases (PDIA3, PDIA6), proline four-hydroxylase, beta peptide (P4HB)], those relevant to protein biosynthesis and translation regulation [eukaryotic translation initiation issue 2 subunit three (EIF2S3), eukaryotic translational elongation factor 2 (EEF2), ribosomal protein L5 (RPL5), Tu translation elongation aspect, mitochondrial (TUFM), ribosomal protein S3 (RPS3), ribophorin I (RPN1), eukaryotic translation elongation aspect one alpha 1 (eEF1A1)], and individuals belong to proteolysis [(proteasome activator subunit 1 (PSME1), calpastatin (Solid)], serpin peptidase inhibitor12181417 clade H (SERPINH1)] and ion transporter group[voltage-dependent anion channel one, 2, and three (VDAC1,VDAC2, VDAC3), chloride intracellular channel 1 (CLIC1), and ATPase Ca++ transporting (ATP2A2)].