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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol four: 330336. 29. Khattri R, Cox T, Yasayko SA, Ramsdell F An critical part for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol four: 337342. 30. Jiang H, Chess L CAL120 Regulation of immune responses by T cells. N Engl J Med 354: 11661176. 31. Akdis M, Verhagen J, Taylor A, Karamloo F, Karagiannidis C, et al. Immune responses in healthy and allergic folks are characterized by a fine balance in between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med 199: 15671575. 32. Macpherson AJ, Lamarre A BLySsful interactions amongst DCs and B cells. Nat Immunol three: 798800. 33. Litinskiy MB, Nardelli B, Hilbert DM, He B, Schaffer A, et al. DCs induce CD40-independent immunoglobulin class CP21 web switching through BLyS and APRIL. Nat Immunol three: 822829. 34. Ng LG, Mackay CR, Mackay F The BAFF/APRIL technique: life beyond B lymphocytes. Mol Immunol 42: 763772. 35. Chaudhuri J, Alt FW Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat Rev Immunol 4: 541 552. 36. Manis JP, Tian M, Alt FW Mechanism and control of class-switch recombination. Trends Immunol 23: 3139. 37. Yu K, Chedin F, Hsieh CL, Wilson TE, Lieber MR R-loops at immunoglobulin class switch regions within the chromosomes of stimulated B cells. Nat Immunol four: 442451. 38. Alfven T, Braun-Fahrlander C, Brunekreef B, von Mutius E, Riedler J, et al. Allergic ailments and atopic sensitization in kids connected to farming and anthroposophic lifestylethe PARSIFAL study. Allergy 61: 414421. 39. Asher MI, Keil U, Anderson HR, Beasley R, Crane J, et al. International Study of Asthma and Allergies in Childhood: rationale and strategies. Eur Respir J 8: 483491. 40. Wickman M, Kull I, Pershagen G, Nordvall SL The BAMSE project: presentation of a potential longitudinal birth cohort study. Pediatr Allergy Immunol 13 Suppl 15: 1113. 41. Riedler J, Braun-Fahrlander C, Eder W, Schreuer M, Waser M, et al. Exposure to farming in early life and improvement of asthma and allergy: a crosssectional survey. Lancet 358: 11291133. 42. Ublagger E, Schreuer M, Eder W, von Mutius E, Benz MR, et al. Validation of inquiries on asthma and wheeze in farming and anthroposophic youngsters. Clin Exp Allergy 35: 10331039. 43. Rosenlund H, Bergstrom A, Alm JS, Swartz J, Scheynius A, et al. Allergic illness and atopic sensitization in children in relation to measles vaccination and measles infection. Pediatrics 123: 771778. 44. Bieli C, Frei R, Schickinger V, Steinle J, Bommer C, et al. Gene expression measurements inside the context of epidemiological research. Allergy 63: 16331636. 45. Benjamini Y, Hochberg Y Controlling the false discovery price: a practical and powerful method to various testing Journal in the royal statistical society B 57: 289300. 46. Eyerich K, Novak N Immunology of atopic eczema: overcoming the Th1/Th2 paradigm. Allergy 68: 974982. 47. Kim HY, DeKruyff RH, Umetsu DT The numerous paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol 11: 577584. 48. Marshall AL, Chetwynd A, Morris JA, Placzek M, Smith C, et al. Type 1 diabetes mellitus in childhood: a matched case manage study in Lancashire and Cumbria, UK. Diabet Med 21: 10351040. 49. Feillet H, Bach JF Improved incidence of inflammatory bowel disease: the cost from the decline of infectious burden Curr Opin Gastroenterol 20: 560564. 50. Loftus EV, Jr. Clinical epidemiology of inflammatory bowel disease: Incidence,.Foxp3 programs the improvement and function of CD4+CD25+ regulatory T cells. Nat Immunol four: 330336. 29. Khattri R, Cox T, Yasayko SA, Ramsdell F An essential function for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol four: 337342. 30. Jiang H, Chess L Regulation of immune responses by T cells. N Engl J Med 354: 11661176. 31. Akdis M, Verhagen J, Taylor A, Karamloo F, Karagiannidis C, et al. Immune responses in healthful and allergic individuals are characterized by a fine balance in between allergen-specific T regulatory 1 and T helper two cells. J Exp Med 199: 15671575. 32. Macpherson AJ, Lamarre A BLySsful interactions in between DCs and B cells. Nat Immunol three: 798800. 33. Litinskiy MB, Nardelli B, Hilbert DM, He B, Schaffer A, et al. DCs induce CD40-independent immunoglobulin class switching via BLyS and APRIL. Nat Immunol three: 822829. 34. Ng LG, Mackay CR, Mackay F The BAFF/APRIL method: life beyond B lymphocytes. Mol Immunol 42: 763772. 35. Chaudhuri J, Alt FW Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat Rev Immunol four: 541 552. 36. Manis JP, Tian M, Alt FW Mechanism and manage of class-switch recombination. Trends Immunol 23: 3139. 37. Yu K, Chedin F, Hsieh CL, Wilson TE, Lieber MR R-loops at immunoglobulin class switch regions inside the chromosomes of stimulated B cells. Nat Immunol four: 442451. 38. Alfven T, Braun-Fahrlander C, Brunekreef B, von Mutius E, Riedler J, et al. Allergic ailments and atopic sensitization in children associated to farming and anthroposophic lifestylethe PARSIFAL study. Allergy 61: 414421. 39. Asher MI, Keil U, Anderson HR, Beasley R, Crane J, et al. International Study of Asthma and Allergies in Childhood: rationale and procedures. Eur Respir J eight: 483491. 40. Wickman M, Kull I, Pershagen G, Nordvall SL The BAMSE project: presentation of a potential longitudinal birth cohort study. Pediatr Allergy Immunol 13 Suppl 15: 1113. 41. Riedler J, Braun-Fahrlander C, Eder W, Schreuer M, Waser M, et al. Exposure to farming in early life and development of asthma and allergy: a crosssectional survey. Lancet 358: 11291133. 42. Ublagger E, Schreuer M, Eder W, von Mutius E, Benz MR, et al. Validation of queries on asthma and wheeze in farming and anthroposophic kids. Clin Exp Allergy 35: 10331039. 43. Rosenlund H, Bergstrom A, Alm JS, Swartz J, Scheynius A, et al. Allergic illness and atopic sensitization in children in relation to measles vaccination and measles infection. Pediatrics 123: 771778. 44. Bieli C, Frei R, Schickinger V, Steinle J, Bommer C, et al. Gene expression measurements within the context of epidemiological research. Allergy 63: 16331636. 45. Benjamini Y, Hochberg Y Controlling the false discovery rate: a practical and powerful strategy to a number of testing Journal on the royal statistical society B 57: 289300. 46. Eyerich K, Novak N Immunology of atopic eczema: overcoming the Th1/Th2 paradigm. Allergy 68: 974982. 47. Kim HY, DeKruyff RH, Umetsu DT The a lot of paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol 11: 577584. 48. Marshall AL, Chetwynd A, Morris JA, Placzek M, Smith C, et al. Variety 1 diabetes mellitus in childhood: a matched case manage study in Lancashire and Cumbria, UK. Diabet Med 21: 10351040. 49. Feillet H, Bach JF Improved incidence of inflammatory bowel illness: the price tag in the decline of infectious burden Curr Opin Gastroenterol 20: 560564. 50. Loftus EV, Jr. Clinical epidemiology of inflammatory bowel disease: Incidence,.

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