Product Name: Anti-CD50 / ICAM-3 Antibody
Description: Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion.
Target:
Conjugate:
Product Category: Mouse Monoclonal Antibody
Immunogen: Stimulated human leukocytes
Host:
Isotype: IgG2b, kappa
Form:
CAS NO: 36098-33-6
Product: F16
Applications: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order Ab without Azide)Flow Cytometry (0.5-1ug/million cells in 0.1ml)Immunofluorescence (0.5-1ug/ml)Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues re
Reactivity: Human. Others not known.
Working Dilution:
Concentration: 0.2mg/ml
Storage: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Species:
Synonyms: ICAMR, Intercellular adhesion molecule 3 (ICAM3)
Background:
Molecular Weight: 110-160kDa
Purity:
Image Description:
PubMed ID:http://aac.asm.org/content/44/6/1660.abstract
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