Sf1670 Pten Inhibitor

Tachycardia, stroke NR 11 NR NRInduces fat reduction, stimulant Ameliorates menopausal symptoms1 2NR Anti-seizure effects (animals) NRAssociated with seizures Possibly connected with seizures NRAntioxidant, cardiovascular, cancer prevention, immune stimulant Prevents cardiovascular illness and cancer, ameliorates GI symptoms, antioxidant, anti-inflammatory Anxiousness, depression, concentration challenges, DM, stimulant, menopausal symptoms, sexual dysfunction in men Cognitive enhancer, prevents cardiovascular disease, antioxidantGI disturbance, dizziness. Possible raise in INR, HTN, arrhythmia. Feasible influence on CYP3A4 and inhibitor of CYP2C9/19 Might enhance risk of bleeding in warfarin customers. Attainable inductor of CYP1A2 and 3A4 Attainable hepatotoxicity enhanced INR, lethargy101May have antiepileptic effects Might have anticonvulsive properties Leaves and stems may be anticonvulsive NR NRNRGinseng [2124,26,28 ]17May exacerbate seizuresGinkgo biloba [2124,26-28 ]GI discomfort, anti-coagulant. May possibly inhibit CYP2B6 and induce CYP3A 1A2, 2C19.16Glucosamine [28 ] Glutamine [28 ]Goldenseal (Hydrastis Canadensis) [23] Grapefruit juice [28 ]Anti-arthritis arthralgia Enhances healing soon after injury, specially GI, promotes muscle constructing Anti-inflammatory, anti-microbialMay raise INR in warfarin users. NR1 1Seeds can be toxic and pro-convulsive. May boost metabolism of AED (PHT, VPA, PB) NR NRPossible hypernatremia, HTN, edema. Sturdy inhibitor of CYP2D6 CYP3A4/5, CYP2E1 Inhibits enteric CYP3A4, possibly increases threat of breast cancer5NRNRPrevents cardiovascular illness and cancer, antioxidant1NRIncreases bioavailability of CBZ, BDZPharmaceuticals 2010, 3 Table 2. Cont.Grape seeds [23,26,28 ] Hops (Humulus lupulus) [23] Kava kava (Piper methysticum) [23,28 ] L-lysine [28 ] Prevents cardiovascular disease and cancer, antioxidant Ameliorates anxiety, insomnia and menopausal symptoms, antiinflammatory, antioxidant Ameliorates depression, anxiety and insomnia, induces local anesthesia Precursor of carnitine, promotes protein constructing, anti-cancer, antiviral Expectorant, anti-viral, antispasmodic, ameliorates gastric duodenal ulcers, and menopausal symptoms Antinociceptive, ameliorates glaucoma, anti-nausea, muscle relaxant, promotes bone health Ameliorates insomnia, circadian rhythm abnormalities, depression, and anxiousness Ameliorates hepatotoxicity and DM, anticancer Antinociceptive, anti-arthritis, antioxidant, diuretic, ameliorates BPH PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20070502 Cardioprotective, ameliorates depression, dementia, ADHD Hypersensitivity, HA, dizziness, nausea. May perhaps inhibit CYP2E1 Sedation. Possibly inhibits CYP2C9, 1A1/2, 1B1 4 1 NR NR NRPossibly exacerbates seizure Possibly exacerbate seizuresPossibly psychosis, choreoathetosis, hepatotoxicity, dermopathy, lymphopenia, GI disturbances, potential for addiction. Inhibitor of CYP2E1, 1A2, induction of 1A1. NR4May benefit1NRNRLicorice (liquorice or Glycyrrhiza glabra) [23] Marijuana (Cannabis sativa) [27] Melatonin [22,23,26,28 ] Milk thistle [28 ] Nettles (Urtica dioica) [28 ] Omega 3/fish oil [27,28 ]In ALS-8176 site overdose – hypokalemia and raise in BP, decrease testosterone in men. Might improve INR when taken with warfarin. Possibly inhibits CYP3A4, 2B6, 2C9. Tachycardia, dry mouth, red eyes, euphoria, anxiety, psychosis, memory deficit. Possibly induces CYP2E1 HA, nausea, somnolence2NRNRMay benefitMay exacerbate seizures7May benefitAssociated with improved seizure frequency NR NRPossible downregulation of CYP3A4, two.