Ate, and cakes. The rs11642841, allocated inside the FTO gene, presented a considerable association with intakes of disaccharides and total power intake and it was one of few alleles to demonstrate a suggestive association (p 0.05) with intakes of SSBs (Figure two and Table S5).Nutrients 2021, 13,7 ofSugars with sweet tasteSweets and chocolateMonosaccharidesDisaccharidesAdded LY294002 References sugarTotal sugarSucroseCarbohydratesTotal energyIce creamAssociated SNP Impact allele Related trait in Hwang et. al. Total sugar intake rs11577403 A rs7424551 GEffect size0.SSBrs35267617 T rs6911544 A rs559904 A rs11642841 C0.0.rs60764613 G rs838145 G rs8103840 C-0.-0.rs838133 A Sweets intake rs2144298 T rs1547578 G rs1358726 T rs4948236 T BMS-8 web rs11607862 T rs11617097 G rs17127497 A Glucose intensity rs76006717 C rs10866646 T rs57083985 T rs4712006 T rs7764197 T rs7456261 A rs4947856 G Fructose intensity rs291958 A rs722311 G rs6494735 T NHDC intensity rs7596758 G rs2192762 A rs6809116 C Aspartame intensity rs1000516 G rs2939710 C rs6909398 A rs4731134 G rs12262926 C rs75941298 A rs55994271 A rs431254 C rs2293698 A rs62208042 G rs72702969 T rs77739585 C rs2010949 C gSweet intensity rs855749 G rs7897266 G rs11062194 C rs9382222 C Sucrose intensity rs10889761 T rs78873212 A rs7602024 A rs995398 C rs7849014 T rs61894278 G rs61905845 G rs8081814 T rs72936627 G Sucrose sweetness rs10205708 G rs1343763 A rs13027837 A rs4441621 T rs9685484 G rs10155613 C rs10113810 A rs4743910 T rs994178 A rs278043 T rs35003134 A rs2834114 T Sucrose liking rs62485870 T rs10953405 A rs1436814 T rs7795216 G rs710411 A rs17127163 A rs11568814 C rs4887033 T Figure 2. Cont. ProteinCakesFatsweetnessrs1343763 A rs13027837 A rs4441621 T rs9685484 G rs10155613 C rs10113810 A Nutrients 2021, 13,rs4743910 T rs994178 A rs278043 T rs35003134 A rs2834114 T Sucrose liking rs62485870 T rs10953405 A rs1436814 T rs7795216 G rs710411 A rs17127163 A rs11568814 C rs4887033 T rs35253088 T rs1497980 T rs62215296 G gSweet. Sucrose intensity rs623965 G rs167132 T rs10762308 G Candidate gene TAS1R2 rs12033832 A rs3935570 T rs35874116 A rs12137730 A rs7534618 T rs9701796 G TAS1R3 rs307355 C rs35744813 C GNAT3 rs7792845 T rs940541 T rs1107660 T rs1107657 T rs1524600 C rs6467217 T rs6970109 C rs6975345 T rs10242727 A rs6467192 G GLUT2 rs5400 C8 of Figure two. Associations involving all principal and secondary SNPs and dietary variables within the MDCS cohort. The effect sizes are presented as /SEE. TAS1R2: Taste receptor kind 1 member 2 gene. TAS1R3: Taste receptor kind 1 member 3 gene. GNAT3: G protein subunit alpha transducin 3. GLUT2: Glucose transporter 2 gene. SEE: Common error from the estimate. MDCS: MalmDiet and Cancer Study. 1 Sucrose and all monosaccharides. 2 Rs2192762 was related to both NHDC and gSweet intensity in Hwang et al. [16]. p 0.05, p 0.005.3.4. Associations amongst Secondary SNPs and All Outcomes A statistically significant inverse association was identified involving the rs5400 C allele (positioned within the GLUT2 gene) and carbohydrate intake, and between the rs167132 T allele (previously connected with gSweet, a weighted mean from the glucose, fructose, NHDC, and aspartame intensity ratings, and sucrose intensity traits within the GWAS performed by Hwang et al. [16]) and total power intake (Figure 2 and Table S5). 3.5. Sensitivity Analyses When the population was stratified based on BMI, the associations for participant.
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