Ent was obtained from all subjects involved in the study. ConflictsEnt was obtained from all

Ent was obtained from all subjects involved in the study. Conflicts
Ent was obtained from all subjects involved in the study. Conflicts of Interest: The authors declare no conflict of interest.
diagnosticsArticleReal-Time Monitoring and Quantitative Evaluation of Resin In-Filtrant Repairing Enamel White Spot Lesions Depending on Optical Coherence TomographySujuan Zeng 1, , Yuhang Huang 1, , Wenyan Huang 1 , Janak L. Pathak 1 , Yanbing He 1 , Weijian Gao 2 , Jing Huang 2 , Yiqing Zhang two , Jian Zhang 2, and Huixian DongDepartment of Pediatric Dentistry, Affiliated Stomatology Hospital of Guangzhou Healthcare University, Guangzhou Crucial Laboratory of Standard and Applied Study of Regenerative Medicine, Guangzhou 510182, China; [email protected] (S.Z.); [email protected] (Y.H.); [email protected] (W.H.); [email protected] (J.L.P.); [email protected] (Y.H.) Division of Biomedical Engineering, School of Basic Healthcare Sciences, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People’s Hospital, Guangzhou Medical University, Guangzhou 511436, China; [email protected] (W.G.); [email protected] (J.H.); [email protected] (Y.Z.) Division of Endodontics, Affiliated Stomatology Hospital of Guangzhou Medical University, Guangzhou Crucial Laboratory of Fundamental and Applied Study of Regenerative Medicine, Guangzhou 510182, China; [email protected] Correspondence: [email protected] These authors contributed equally within this study.Citation: Zeng, S.; Huang, Y.; Huang, W.; Pathak, J.L.; He, Y.; Gao, W.; Huang, J.; Zhang, Y.; Zhang, J.; Dong, H. Real-Time Monitoring and Quantitative Evaluation of Resin In-Filtrant Repairing Enamel White Spot Lesions According to Optical Coherence Tomography. Diagnostics 2021, 11, 2046. https://doi.org/ ten.3390/diagnostics11112046 Academic Editor: Luca Testarelli Received: 23 August 2021 Accepted: 2 November 2021 Published: four NovemberAbstract: The aim with the present study was to explore the feasibility of real-time monitoring and quantitative guiding the repair of enamel white spot lesions (WSLs) with resin infiltration by optical coherence tomography (OCT). Seven New Zealand rabbits had been treated with 37 phosphoric acid etchant for 15 min to establish the model of enamel demineralization chalk spots of upper incisors, which were repaired by Icon resin infiltrant. OCT, stereo microscope (SM) imaging, scanning electron microscope (SEM) imaging and hematoxylin eosin (HE) staining have been made use of to image each operation step. The modifications of WSLs of enamel just before and in the course of action of restoration with resin Seclidemstat Inhibitor infiltrant showed specific overall performance in OCT pictures, which have been constant with all the corresponding MCC950 web results of stereomicroscope and SEM. OCT can non-invasively and accurately image the whole procedure of repairing enamel demineralization layer with resin infiltration real-time, which can effectively guide the clinical use of resin infiltrant to repair enamel WSLs and be applied as an imaging tool to evaluate the course of action and impact of restoration with resin infiltrant in the similar time. Key phrases: enamel; OCT; resin infiltrant; white spot lesionsPublisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.1. Introduction Orthodontic brackets or plaque accumulation demineralize the tooth surface, leaving white spot lesions (WSLs) [1]. As an early and reversible type of dental caries, WSLs negatively have an effect on the aesthetics and dental appearance in the tooth [6]. Present clini.