Product Name :
AOH1160
Description:
AOH1160 is a potent, first-in-class, orally available small molecule proliferating cell nuclear antigen (PCNA) inhibitor, interferes with DNA replication, blocks homologous recombination-mediated DNA repair, causes cell-cycle arrest and induces apoptosis. AOH1160 selectively kills many types of cancer cells (mean GI50=330 nM) without causing significant toxicity to a broad range of nonmalignant cells.
CAS:
2089314-57-6
Molecular Weight:
396.44
Formula:
C25H20N2O3
Chemical Name:
2-[(naphthalen-1-yl)formamido]-N-(2-phenoxyphenyl)acetamide
Smiles :
O=C(NCC(=O)NC1=CC=CC=C1OC1C=CC=CC=1)C1=CC=CC2=CC=CC=C21
InChiKey:
COPRLRLXDBSLET-UHFFFAOYSA-N
InChi :
InChI=1S/C25H20N2O3/c28-24(17-26-25(29)21-14-8-10-18-9-4-5-13-20(18)21)27-22-15-6-7-16-23(22)30-19-11-2-1-3-12-19/h1-16H,17H2,(H,26,29)(H,27,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{AEE788} site|{AEE788} Apoptosis|{AEE788} Biological Activity|{AEE788} In stock|{AEE788} custom synthesis|{AEE788} Autophagy}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
AOH1160 is a potent, first-in-class, orally available small molecule proliferating cell nuclear antigen (PCNA) inhibitor, interferes with DNA replication, blocks homologous recombination-mediated DNA repair, causes cell-cycle arrest and induces apoptosis.{{Efonidipine hydrochloride monoethanolate} MedChemExpress|{Efonidipine hydrochloride monoethanolate} Neuronal Signaling|{Efonidipine hydrochloride monoethanolate} Protocol|{Efonidipine hydrochloride monoethanolate} References|{Efonidipine hydrochloride monoethanolate} custom synthesis|{Efonidipine hydrochloride monoethanolate} Cancer} AOH1160 selectively kills many types of cancer cells (mean GI50=330 nM) without causing significant toxicity to a broad range of nonmalignant cells.PMID:25016614 |Product information|CAS Number: 2089314-57-6|Molecular Weight: 396.44|Formula: C25H20N2O3|Chemical Name: 2-[(naphthalen-1-yl)formamido]-N-(2-phenoxyphenyl)acetamide|Smiles: O=C(NCC(=O)NC1=CC=CC=C1OC1C=CC=CC=1)C1=CC=CC2=CC=CC=C21|InChiKey: COPRLRLXDBSLET-UHFFFAOYSA-N|InChi: InChI=1S/C25H20N2O3/c28-24(17-26-25(29)21-14-8-10-18-9-4-5-13-20(18)21)27-22-15-6-7-16-23(22)30-19-11-2-1-3-12-19/h1-16H,17H2,(H,26,29)(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
