Product Name :
BAY K 8644
Description:
Bay K 8644 is a potent selective activator of L-type Ca2 channel with IC50 of 173 nM
CAS:
71145-03-4
Molecular Weight:
356.30
Formula:
C16H15F3N2O4
Chemical Name:
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate
Smiles :
COC(=O)C1C(C(=C(C)NC=1C)[N+]([O-])=O)C1=CC=CC=C1C(F)(F)F
InChiKey:
ZFLWDHHVRRZMEI-UHFFFAOYSA-N
InChi :
InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Tiragolumab} MedChemExpress|{Tiragolumab} Biological Activity|{Tiragolumab} In Vivo|{Tiragolumab} supplier|{Tiragolumab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Tamibarotene} medchemexpress|{Tamibarotene} Vitamin D Related/Nuclear Receptor|{Tamibarotene} Technical Information|{Tamibarotene} Description|{Tamibarotene} supplier|{Tamibarotene} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bay K 8644 is a potent selective activator of L-type Ca2 channel with IC50 of 173 nM|Product information|CAS Number: 71145-03-4|Molecular Weight: 356.30|Formula: C16H15F3N2O4|Chemical Name: methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate|Smiles: COC(=O)C1C(C(=C(C)NC=1C)[N+]([O-])=O)C1=CC=CC=C1C(F)(F)F|InChiKey: ZFLWDHHVRRZMEI-UHFFFAOYSA-N|InChi: InChI=1S/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO: 71 mg/mL(199.27 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23710097 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Bay K 8644 increases resting tension in segments of mesenteric arteries isolated from young and old rats as an agonist of L-type Ca2+ channel.|In Vivo:|Bay K 8644 induces small contractions in aortae from Wistar-Kyoto(WKY) rats of 5-week-, 3-month-, 1-year-, 1.5-year-old, which are unaltered with age.|References:|Hernández MC，et al. J Auton Pharmacol. 1995, 15(4):257-269.Sulayma A. Albarwani,et al. Front Physiol. 2016, 7:171.A J Gonzales,et al. Br J Pharmacol. 1989, 96(2):333-340Products are for research use only. Not for human use.|
