Product Name :
Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4)
Applications:
Internalization Test
Reactivity :
Mouse IgG
Conjugate:
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) is designed for studying on the internalization of antibodies. Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) is based on recombinant single domain antibodies to mouse IgG Fc coupled to VcDXD. Based on immunoelectrophoresis and/or ELISA, Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) reacts with the Fc fragment of mouse IgG(including mouse IgG1, IgG2a, IgG2b) heavy chain but not with the Fab portion of mouse IgG. Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) is an effective detection tool and can be used as a useful tool for the evaluation of antibody potency prior to ADCs. | Immunogen: Recombinant mouse IgG | Host: Alpaca pacous | Isotype: VHH domain of alpaca IgG2b/2c | Conjugate: VcDXD(2 moles VcDXD per mole VHH) | Specificity: Mouse IgG(Fcγ fragment specific) | Cross-Reactivity: No cross-reactivity with mouse IgM, rabbit, human, cynomolgus, rat, goat IgG | Purity: Recombinant Expression and Affinity purified | Concentration: 0.5mg/ml | Formation: Liquid, 10mM PBS (pH 7.4) | Storage: Store at –20 °C(Avoid freeze / thaw cycles) | Background:VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(
Description2 :
Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) is designed for studying on the internalization of antibodies. Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) is based on recombinant single domain antibodies to mouse IgG Fc coupled to VcDXD.{{3036981-21-9} web|{3036981-21-9} Purity & Documentation|{3036981-21-9} References|{3036981-21-9} manufacturer} Based on immunoelectrophoresis and/or ELISA, Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) reacts with the Fc fragment of mouse IgG(including mouse IgG1, IgG2a, IgG2b) heavy chain but not with the Fab portion of mouse IgG.{{10047-33-3} medchemexpress|{10047-33-3} Biological Activity|{10047-33-3} In Vivo|{10047-33-3} manufacturer} Anti-Mouse IgG, AlpSdAbs® VHH(VcDXD ×4) is an effective detection tool and can be used as a useful tool for the evaluation of antibody potency prior to ADCs.PMID:28846233
Immunogen:
Recombinant mouse IgG
Host :
Alpaca pacous
Isotype:
VHH domain of alpaca IgG2b/2c
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C(Avoid freeze / thaw cycles)
Function:
Antibody Internalization Test: 2ug per 10ug test antibody (molar ratio=2:1).Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.
