Product Name :
Olinciguat
Description:
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay.
CAS:
1628732-62-6
Molecular Weight:
509.39
Formula:
C21H16F5N7O3
Chemical Name:
(2R)-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino]-2-hydroxy-2-(trifluoromethyl)propanamide
Smiles :
NC(=O)[C@](O)(CNC1=NC(=NC=C1F)C1C=C(C2C=CON=2)N(CC2=CC=CC=C2F)N=1)C(F)(F)F
InChiKey:
YWQFJNWMWZMXRW-HXUWFJFHSA-N
InChi :
InChI=1S/C21H16F5N7O3/c22-12-4-2-1-3-11(12)9-33-16(14-5-6-36-32-14)7-15(31-33)18-28-8-13(23)17(30-18)29-10-20(35,19(27)34)21(24,25)26/h1-8,35H,9-10H2,(H2,27,34)(H,28,29,30)/t20-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Charybdotoxin} site|{Charybdotoxin} Inhibitor|{Charybdotoxin} TGF-beta/Smad|{Charybdotoxin} Technical Information|{Charybdotoxin} Formula|{Charybdotoxin} manufacturer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay.{{Pyrimethamine} web|{Pyrimethamine} Cell Cycle/DNA Damage|{Pyrimethamine} Protocol|{Pyrimethamine} In Vitro|{Pyrimethamine} custom synthesis|{Pyrimethamine} Epigenetics} |Product information|CAS Number: 1628732-62-6|Molecular Weight: 509.PMID:32515635 39|Formula: C21H16F5N7O3|Chemical Name: (2R)-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino]-2-hydroxy-2-(trifluoromethyl)propanamide|Smiles: NC(=O)[C@](O)(CNC1=NC(=NC=C1F)C1C=C(C2C=CON=2)N(CC2=CC=CC=C2F)N=1)C(F)(F)F|InChiKey: YWQFJNWMWZMXRW-HXUWFJFHSA-N|InChi: InChI=1S/C21H16F5N7O3/c22-12-4-2-1-3-11(12)9-33-16(14-5-6-36-32-14)7-15(31-33)18-28-8-13(23)17(30-18)29-10-20(35,19(27)34)21(24,25)26/h1-8,35H,9-10H2,(H2,27,34)(H,28,29,30)/t20-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (245.39 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
