Product Name :
Bosutinib D8
Description:
Bosutinib D8 (SKI-606 D8) is a deuterium labeled Bosutinib. Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively.
CAS:
Molecular Weight:
538.50
Formula:
C26H29Cl2N5O3
Chemical Name:
4-((2, 4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl-2, 2, 3, 3, 5, 5, 6, 6-d8)propoxy)quinoline-3-carbonitrile
Smiles :
[2H]C1([2H])N(CCCOC2C=C3N=CC(C#N)=C(NC4=CC(OC)=C(Cl)C=C4Cl)C3=CC=2OC)C([2H])([2H])C([2H])([2H])N(C)C1([2H])[2H]
InChiKey:
UBPYILGKFZZVDX-COMRDEPKSA-N
InChi :
InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)/i6D2,7D2,8D2,9D2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Bosutinib D8 (SKI-606 D8) is a deuterium labeled Bosutinib. Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively.|Product information|Molecular Weight: 538.50|Formula: C26H29Cl2N5O3|Chemical Name: 4-((2, 4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl-2, 2, 3, 3, 5, 5, 6, 6-d8)propoxy)quinoline-3-carbonitrile|Smiles: [2H]C1([2H])N(CCCOC2C=C3N=CC(C#N)=C(NC4=CC(OC)=C(Cl)C=C4Cl)C3=CC=2OC)C([2H])([2H])C([2H])([2H])N(C)C1([2H])[2H]|InChiKey: UBPYILGKFZZVDX-COMRDEPKSA-N|InChi: InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)/i6D2,7D2,8D2,9D2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.QX-314 custom synthesis |Shelf Life: ≥12 months if stored properly.Thiostrepton web |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32491691 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
