Product Name :
GLP-1 receptor agonist 1
Description:
GLP-1 receptor agonist 1 is a GLP-1 receptor agonist extracted from patent WO2018056453A1, Compound 67.
CAS:
2212020-52-3
Molecular Weight:
882.96
Formula:
C48H48F2N10O5
Chemical Name:
3-[(1S,2S)-1-5-[(4S)-2,2-dimethyloxan-4-yl]-2-[(4S)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-2H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carbonyl]-1H-indol-1-yl-2-methylcyclopropyl]-4,5-dihydro-1,2,4-oxadiazol-5-one
Smiles :
CC1(C)C[C@H](CCO1)C1C=C2C=C(C(=O)N3CCC4=NN(C(=C4[C@@H]3C)N3C=CN(C4=CC=C5C(C=NN5C)=C4F)C3=O)C3=CC(C)=C(F)C(C)=C3)N(C2=CC=1)[C@]1(C[C@@H]1C)C1NC(=O)ON=1
InChiKey:
USUWIEBBBWHKNI-KHIFEHGGSA-N
InChi :
InChI=1S/C48H48F2N10O5/c1-25-18-32(19-26(2)40(25)49)60-42(58-16-15-57(46(58)63)37-11-10-36-33(41(37)50)24-51-55(36)7)39-28(4)56(14-12-34(39)53-60)43(61)38-21-31-20-29(30-13-17-64-47(5,6)23-30)8-9-35(31)59(38)48(22-27(48)3)44-52-45(62)65-54-44/h8-11,15-16,18-21,24,27-28,30H,12-14,17,22-23H2,1-7H3,(H,52,54,62)/t27-,28-,30-,48-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GLP-1 receptor agonist 1 is a GLP-1 receptor agonist extracted from patent WO2018056453A1, Compound 67.|Product information|CAS Number: 2212020-52-3|Molecular Weight: 882.96|Formula: C48H48F2N10O5|Chemical Name: 3-[(1S,2S)-1-5-[(4S)-2,2-dimethyloxan-4-yl]-2-[(4S)-3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-2H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carbonyl]-1H-indol-1-yl-2-methylcyclopropyl]-4,5-dihydro-1,2,4-oxadiazol-5-one|Smiles: CC1(C)C[C@H](CCO1)C1C=C2C=C(C(=O)N3CCC4=NN(C(=C4[C@@H]3C)N3C=CN(C4=CC=C5C(C=NN5C)=C4F)C3=O)C3=CC(C)=C(F)C(C)=C3)N(C2=CC=1)[C@]1(C[C@@H]1C)C1NC(=O)ON=1|InChiKey: USUWIEBBBWHKNI-KHIFEHGGSA-N|InChi: InChI=1S/C48H48F2N10O5/c1-25-18-32(19-26(2)40(25)49)60-42(58-16-15-57(46(58)63)37-11-10-36-33(41(37)50)24-51-55(36)7)39-28(4)56(14-12-34(39)53-60)43(61)38-21-31-20-29(30-13-17-64-47(5,6)23-30)8-9-35(31)59(38)48(22-27(48)3)44-52-45(62)65-54-44/h8-11,15-16,18-21,24,27-28,30H,12-14,17,22-23H2,1-7H3,(H,52,54,62)/t27-,28-,30-,48-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (141.Fmoc-Thr(tBu)-OH supplier 57 mM; Need ultrasonic).Iptacopan Purity |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33136224 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|GLP-1 is an incretin secreted from L cells of the small intestine when nutrients pass through the digestive tract, and glucose is transmitted via the GLP-1 receptor. GLP-1 exhibits various actions such as dependent gastric emptying delay, and feeding suppression.|Products are for research use only. Not for human use.|
