Product Name :
Rabbit anti-AP3S1 Polyclonal Antibody(N-term)
Synonym :
AP-3 complex subunit sigma-1; AP-3 complex subunit sigma-3A; Adaptor-related protein complex 3 subunit sigma-1; Clathrin-associated/assembly/adaptor protein; small 3; Sigma-3A-adaptin; Sigma3A-adaptin; Sigma-adaptin 3a; AP3S1; CLAPS3
Host :
Rabbit
Species Reactivity:
Human, Mouse
Specificity :
This AP3S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AP3S1.
Predicted Reactivity:
Bovine
Applications :
WB~~1:1000IHC-P~~1:50~100
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
Signal Transduction
Background :
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
UniProt :
Q92572
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Description Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |Synonym AP-3 complex subunit sigma-1; AP-3 complex subunit sigma-3A; Adaptor-related protein complex 3 subunit sigma-1; Clathrin-associated/assembly/adaptor protein; small 3; Sigma-3A-adaptin; Sigma3A-adaptin; Sigma-adaptin 3a; AP3S1; CLAPS3 |Host Rabbit |Specificity This AP3S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AP3S1. |Species Reactivity Human, Mouse |Predicted Reactivity Bovine |Applications WB~~1:1000IHC-P~~1:50~100 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long term storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas Signal Transduction |Target |Background Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |Cellular localization Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex |UniProt Q92572 |References |References Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Zhou, J.B., et al. Med. Sci. Monit. 16 (6), BR179-BR183 (2010) :Lefrancois, S., et al. Dev. Cell 7(4):619-625(2004)Salazar, G., et al. Mol. Biol. Cell 15(2):575-587(2004)Nie, Z., et al. Dev. Cell 5(3):513-521(2003) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-AP3S1 Polyclonal Antibody(N-term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
841205-47-8 MedChemExpress 320-67-2 manufacturer PMID:31297516 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
